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Join the registry even before you have identified a suitable case, as contract formalities may delay patient data entry.

Welcome to SAPFIRE –
Europe’s registry on sepsis-associated Purpura fulminans

The International SAPFIRE registry will help extend knowledge on sepsis-associated Purpura fulminans. It’s a prospective multicenter registry derived from systematic data collection on the incidence and treatment of sepsis-associated Purpura fulminans.



Sepsis-Associated Purpura Fulminans International Registry – Europe

See Our Study Protocol



Clinicaltrials.gov Identifier: NCT02238795

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Our Members

SapFire would not be possible without the support of our members. … Click here to view SapFire’s members

See All Our Members


Our Team

Our SAPFIRE Team. This is where you can find out about the team and who work behind the scenes

See Our Team